Recombinant HRAS antibody (AA 50-100)

Catalog No. ABIN7795737

The Rabbit Monoclonal anti-HRAS antibody has been validated for WB and FACS. It is suitable to detect HRAS in samples from Human and Mouse.

Quick Overview for Recombinant HRAS antibody (AA 50-100) (ABIN7795737)

Target: HRAS (HRas proto-oncogene, GTPase (HRAS))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HRAS antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: BLR321M

Product Details anti-HRAS Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-K-Ras Recombinant Monoclonal Antibody [BLR321M]

Purification: Purified

Immunogen: between 50 and 100

Isotype: IgG

Application Details

Application Notes: WB,11,000,Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for HRAS

Target: HRAS (HRas proto-oncogene, GTPase (HRAS))

Alternative Name: K-Ras

Background: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. K-ras plays an important role in the regulation of cell proliferation and plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P01116].

Gene ID: 3845

UniProt: P01116

Pathways: p53 Signaling, MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling